2. Nonopioid analgesic drugs. Physicians involved in perioperative care, as well as chronic pain caregivers, are increasingly turning toward the use of nonopioid analgesic drugs (Table 1) [Citation 17, Citation 18].Recent advances in the pharmacological management of acute and chronic pain are not the result of new 'miracle' drugs, but often new preparations and ways to use 'old drugs.. Types of Non-Opioid Analgesics. Non-opioid analgesics can be classified into three main categories: NSAIDs, acetaminophen, and topical agents. NSAIDs are the most commonly used non-opioid analgesics. 32 They work by inhibiting the production of prostaglandins, which are responsible for pain and inflammation. 33 NSAIDs can be further classified into two categories: selective and non-selective.

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Let's review six non-opioid medications for pain relief. This way, you can choose a safe and effective long-term treatment plan that works for you. 1. Acetaminophen. Acetaminophen, the active ingredient in Tylenol, is an over-the-counter (OTC) medication that's good for relieving headaches, back pain, and arthritis pain.. The use of multimodal opioid-sparing analgesia is a key concept and a guiding principle for acute pain management, including perioperative pain. Multimodal analgesia may include nonpharmacologic strategies, local and regional anesthesia techniques, nonopioid analgesics, and opioids only when necessary. This topic will discuss the various.